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Susanne Neumann Selected Research

Thyrotropin Receptors (Thyrotropin Receptor)

1/2022Graves' Autoantibodies Exhibit Different Stimulating Activities in Cultures of Thyrocytes and Orbital Fibroblasts Not Reflected by Clinical Assays.
12/2020Targeting TSH and IGF-1 Receptors to Treat Thyroid Eye Disease.
1/2020TSH/IGF1 receptor crosstalk: Mechanism and clinical implications.
1/2020β-Arrestin 1 in Thyrotropin Receptor Signaling in Bone: Studies in Osteoblast-Like Cells.
1/2019Arrestin-β-1 Physically Scaffolds TSH and IGF1 Receptors to Enable Crosstalk.
10/2018Stimulatory TSH-Receptor Antibodies and Oxidative Stress in Graves Disease.
1/2018Evidence That Graves' Ophthalmopathy Immunoglobulins Do Not Directly Activate IGF-1 Receptors.
1/2017Inhibiting thyrotropin/insulin-like growth factor 1 receptor crosstalk to treat Graves' ophthalmopathy: studies in orbital fibroblasts in vitro.
1/2016An Enantiomer of an Oral Small-Molecule TSH Receptor Agonist Exhibits Improved Pharmacologic Properties.
1/2016TSH/IGF-1 Receptor Cross Talk in Graves' Ophthalmopathy Pathogenesis.
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Susanne Neumann Research Topics

Disease

14Graves Ophthalmopathy
01/2022 - 08/2012
9Graves Disease (Basedow Disease)
12/2020 - 11/2002
6Hyperthyroidism
01/2022 - 12/2008
6Thyroid Neoplasms (Thyroid Cancer)
01/2016 - 11/2002
3Type 2 Diabetes Mellitus (MODY)
02/2008 - 06/2007
2Thyroid Diseases (Thyroid Disease)
01/2014 - 11/2002
2Hypothyroidism
08/2011 - 01/2004
2Neoplasm Metastasis (Metastasis)
11/2009 - 11/2002
2Goiter
05/2006 - 11/2003
1Autoimmune Diseases (Autoimmune Disease)
12/2020
1Multiple Sclerosis
11/2020
1Brain Neoplasms (Brain Tumor)
01/2020
1Stroke (Strokes)
01/2020
1Infections
01/2020
1Osteosarcoma (Osteogenic Sarcoma)
01/2020
1Neuroinflammatory Diseases
01/2019
1Ischemia
01/2016
1Fibrous Dysplasia of Bone
01/2014
1Polyostotic Fibrous Dysplasia (McCune Albright Syndrome)
01/2014
1Bullous Pemphigoid (Pemphigoid)
12/2010
1Melanoma (Melanoma, Malignant)
11/2009
1Neoplasms (Cancer)
11/2009
1Diabetes Mellitus
06/2008
1Graft vs Host Disease (Graft-Versus-Host Disease)
03/2007
1Nonautoimmune Hyperthyroidism
05/2006
1Thyroid Nodule (Nodule, Thyroid)
02/2004
1Acromegaly
01/2004
1Hyperparathyroidism
01/2004
1Multiple Endocrine Neoplasia Type 2a (MEN 2)
01/2004
1Endemic Goiter
11/2003
1Reactive Arthritis (Reiter Disease)
06/2003
1Immune Reconstitution Inflammatory Syndrome
06/2003
1Euthyroid Goiter
11/2002
1Hyperaldosteronism (Conn Syndrome)
03/2002
1Fibrosis (Cirrhosis)
03/2002
1Obesity
01/2002
1Insulin Resistance
01/2002

Drug/Important Bio-Agent (IBA)

18Thyrotropin Receptors (Thyrotropin Receptor)IBA
01/2022 - 02/2003
5IGF Type 1 Receptor (IGF 1 Receptor)IBA
01/2022 - 03/2015
5AutoantibodiesIBA
01/2022 - 08/2012
4AntibodiesIBA
01/2022 - 12/2008
4Messenger RNA (mRNA)IBA
01/2020 - 01/2002
4Thyrotropin (Thyroid-Stimulating Hormone)FDA Link
01/2018 - 11/2009
4Pharmaceutical PreparationsIBA
01/2016 - 10/2007
3Hyaluronic Acid (Hyaluronan)IBA
01/2019 - 05/2013
3Nonesterified Fatty Acids (NEFA)IBA
06/2008 - 06/2007
2Thyroid HormonesIBA
12/2020 - 08/2011
2Thyroid-Stimulating ImmunoglobulinsIBA
12/2020 - 02/2011
2Insulin-Like PeptidesIBA
09/2020 - 01/2017
2Thyrotropin AlfaFDA LinkGeneric
11/2009 - 07/2009
2Insulin (Novolin)FDA Link
10/2007 - 01/2002
2Glucose (Dextrose)FDA LinkGeneric
10/2007 - 03/2002
2Proteins (Proteins, Gene)FDA Link
02/2004 - 01/2002
2ThyroglobulinFDA Link
11/2003 - 11/2002
1teprotumumabIBA
01/2022
1Biomarkers (Surrogate Marker)IBA
11/2020
1tetraiodothyroacetic acid (TA(4))IBA
01/2019
1Superoxides (Superoxide)IBA
10/2018
1ZymosanIBA
10/2018
1phorbolIBA
10/2018
12-hydroxyethidiumIBA
10/2018
1Immunoglobulins (Immunoglobulin)IBA
01/2018
1CaspasesIBA
01/2016
1GTP-Binding Proteins (G-Protein)IBA
01/2014
1Long-Acting Thyroid Stimulator (LATS)IBA
05/2013
1FIBSIBA
08/2012
1HLA-DR Antigens (HLA-DR)IBA
12/2010
1Biological ProductsIBA
11/2009
1EnzymesIBA
11/2009
1Matrix Metalloproteinases (MMPs)IBA
11/2009
1LigandsIBA
12/2008
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
02/2008
1Capsules (Microcapsules)IBA
03/2007
1Thyroxine (Levothyroxine)FDA LinkGeneric
05/2006
1IodidesIBA
02/2004
1sodium-iodide symporter (sodium iodide symporter)IBA
02/2004
1Pentagastrin (Peptavlon)FDA Link
01/2004
1Calcitonin (Calcitonin, Eel)FDA LinkGeneric
01/2004
1Codon (Codons)IBA
01/2004
1SymportersIBA
11/2003
1IodineIBA
11/2003
1Doxycycline (Periostat)FDA LinkGeneric
06/2003
1RNA (Ribonucleic Acid)IBA
11/2002
1AldosteroneIBA
03/2002
1AdipokinesIBA
01/2002
1Hormones (Hormone)IBA
01/2002
1AdiponectinIBA
01/2002

Therapy/Procedure

2Therapeutics
03/2015 - 11/2002
1Ligation
01/2020
1Radiotherapy
01/2020
1Cranial Irradiation
01/2020
1Transplantation
01/2019
1Intradermal Injections
11/2009
1Thyroidectomy
11/2002